cis-Urocanic acid
CAS No. 7699-35-6
cis-Urocanic acid ( (Z)-Urocanic acid; cis-UCA; (E)-Urocanic acid; (Z)-Imidazole-4-acrylic acid; (Z)-3-(1H-Imidazol-5-yl)acrylic acid )
Catalog No. M26118 CAS No. 7699-35-6
cis-Urocanic acid is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 417 | Get Quote |
|
10MG | 615 | Get Quote |
|
25MG | 963 | Get Quote |
|
50MG | 1305 | Get Quote |
|
100MG | 1755 | Get Quote |
|
500MG | 3501 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product Namecis-Urocanic acid
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NoteResearch use only, not for human use.
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Brief Descriptioncis-Urocanic acid is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.
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Descriptioncis-Urocanic acid is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.(In Vitro):Treatment with 100 μg/mL cis-Urocanic acid completely suppresses IL-6 and IL-8 secretion decreases caspase-3 activity and improves cell viability against UV-B irradiation. No significant effects on IL-6 or IL-8 secretion, caspase-3 activity, or viability of the non-irradiated cells are observed with 100 μg/mL cis-Urocanic acid in both cell types .
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Synonyms(Z)-Urocanic acid; cis-UCA; (E)-Urocanic acid; (Z)-Imidazole-4-acrylic acid; (Z)-3-(1H-Imidazol-5-yl)acrylic acid
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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RecptorAlkyl-Chain
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Research Area——
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Indication——
Chemical Information
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CAS Number7699-35-6
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Formula Weight138.1
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Molecular FormulaC6H6N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESOC(=O)\C=C/c1cnc[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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